Calf-Guard, an oral vaccination for newborn calves or intramuscular vaccineation of pregnant cows, aids in the prevention of diarrhea caused by bovine rotaviurs and coronavirus. Calf-Guard stimulates maternal antibodies, that trnsfer to nursing calves via colosturm and milk. Oral vaccination, 3 mL dose, of calves should occur as soon as possible after birth before ingestion of colostrum. Two doses of 3 mL should be administered 3-6 weeks apart during late pregnancy. The second does should be administered within 30 days prior to calving for best results, with an annual revaccination of two doses during each subsequent pregnancy.