NOW Bromelain 2400 GDU/g is one of the highest natural potencies of this proteolytic (protein-digesting) enzyme available. While most enzymes are generally considered to be poorly absorbed, Bromelain is one of the most bioavailable of all enzymes and has been the subject of numerous studies worldwide. Although Bromelain is derived from pineapples, supplementation is necessary to achieve optimum levels of this enzyme. Encapsulated in Vcaps for a 100% vegetarian formula.
Take 1 Vcap with or between meals.
Serving Size: 1 Vcap Servings per Container: 120
|Ingredients||Amount per Serving||% Daily Value|
|Bromelain (2400 GDU/g) †||500 mg||*|
|* Percent Daily Values are based on 2,000 calorie diet.|
|† Daily Value not established|
Other Ingredients: Cellulose (capsule), Maltodextrin, Rice Flour and Magnesium Stearate (vegetable source).
Contains no: sugar, salt, yeast, wheat, gluten, soy, milk, egg, shellfish or preservatives. Vegetarian/Vegan Product.
† Gelatin Digesting Units - a measure of proteolytic (protein digesting) activity.
Vcaps® is a registered trademark of Capsugel.
Store in a cool, dry place.
Your Bromelain tablets are labeled as having a potency of 2000 gdu/gram, yet I see that the Bromelain in your Plant Enzyme Complex is labeled as FCC (PU) units. What is the difference and is there a conversion between the two?
The measurement of enzymatic activity is very complex. Bromelain can be standardized using different activity-measuring units, including Milk Clot Units (MCU/mg), Casein Digestion Units (CDU/mg), Bromelain Tyrosine Units (BTU/gram), Rorer units, FCC Papain units (PU), and more.
In an assay one FCC Papain Unit (PU), for example, is defined as that quantity of enzyme that liberates the equivalent of 1 µg (or mcg - microgram) of tyrosine per hour under the conditions of the assay. This procedure is also used to determine the proteolytic (protein-digesting) activity of ficin and bromelain. The assay is based on a 60-min proteolytic hydrolysis of a casein substrate at pH 6.0 and 40° C. Soluble casein is then measured spectrophotometrically at 280 nm (nanometers).
Different activity-measuring methods can use different protein substrates as well as methods. Since enzymes are specific to peptide bonds, as well as which terminal end of an amino acid it will cleave, there typically will not be a conversion between measures unless both measures are performed. This is why conversion among different enzyme measures can be so difficult.
In the case of the single ingredient formula, Bromelain at 2000 GDU/g (gelatin-digesting units/gram) would be equal to a 30,000,000 FCC PU/g potency.