Studies show Comfort Zone with D.A.P. products:

Help reduce destructive behavior in 91% of dogs
Help reduce house soiling in 75% of dogs
Help reduce excessive barking and whimpering in 65% of dogs
Comfort Zone with D.A.P. products help in many other stressful situations as well, such as:

Introducing a puppy to a new home
Loud noises, such as fireworks and thunderstorms
Being left home alone
Traveling